TIGIT Protein (C-human IgG1-Fc, Cynomolgus)

Product Specifications

Abbreviation

TIGIT

Host

HEK 293

Tag

C-human IgG1-Fc

Endotoxin

< 1.0 EU per μg protein as determined by the LAL method.

Purity

≥ 90 % as determined by SDS-PAGE.

Bioactivity

1.Immobilized human CD155/PVR Protein, Human, Recombinant (ECD, His Tag) (10109-H08H) at 2μg/mL (100μL/well) can bind TIGIT Protein, Cynomolgus, Recombinant (ECD, hFc Tag) (90890-C02H), the EC50 of TIGIT Protein, Cynomolgus, Recombinant (ECD, hFc Tag) (90890-C02H) is 5-30 ng/mL (Routinely tested) . 2.Loaded Recombinant Cynomolgus TIGIT Protein, hFc Tag (Cat. No. 90890-C02H) on proA Biosensor, can bind Recombinant Rhesus CD155/PVR Protein, His Tag (Cat. No. 90005-C08H) with an affinity constant of 0.964 μM as determined in BLI assay (Sartorius Octet RED384) (Routinely tested) . 3.Immobilized Recombinant Rhesus CD155 / PVR Protein (His Tag) (Cat: 90005-C08H) at 5 μg/mL (100 μL/well) can bind Recombinant Cynomolgus TIGIT / VSTM3 Protein (Fc Tag) (Cat: 90890-C02H), the EC50 is 20-60 ng/mL (QC tested) .