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TIGIT Protein (C-human IgG1-Fc & AVI, Human)

Product Specifications

Abbreviation

TIGIT

Synonyms

DKFZp667A205, FLJ39873, VSIG9, VSTM3, WUCAM

Host

HEK 293

Tag

C-human IgG1-Fc & AVI

Endotoxin

< 1.0 EU per μg protein as determined by the LAL method.

Purity

≥ 90 % as determined by SDS-PAGE. ≥ 95 % as determined by SEC-HPLC.

Bioactivity

1.Immobilized Recombinant Human CD155 / PVR / NECL5 Protein (Fc Tag) (Cat: 10109-H02H) at 5 μg/mL (100 μL/well) can bind Recombinant Human TIGIT Protein (ECD, Fc & AVI Tag), Biotinylated (Cat: 10917-H41H-B), the EC50 is 15-45 ng/mL (QC tested) . 2.Immobilized Anti-Tigit (Research grade Tiragolumab biosimilar) at 2 μg/mL (100 μL/well) can bind Recombinant Human TIGIT Protein (ECD, Fc & AVI Tag), Biotinylated (Cat: 10917-H41H-B), the EC50 is 1.6-5 ng/mL (Routinely tested) .

Function

Met1-Pro141

Molecular Weight

The recombinant human TIGIT consists of 373 amino acids and predicts a molecular mass of 41.6 kDa. As a result of glycosylation, it migrates as an approximately 49.2 kDa band in SDS-PAGE under reducing conditions.

Species

Human

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