TIGIT Protein (C-His, Human)

Product Specifications

Abbreviation

TIGIT

Synonyms

DKFZp667A205, FLJ39873, VSIG9, VSTM3, WUCAM

Host

HEK 293

Tag

C-His

Endotoxin

< 1.0 EU per μg protein as determined by the LAL method.

Purity

> 90 % as determined by SDS-PAGE.>90% as determined by SEC-HPLC

Bioactivity

1.Immobilized Human TIGIT His (Cat:10917-H08H2) at 2 μg/mL (100 μL/well) can bind Human CD155/PVR hFc (Cat:10109-H02H), the EC50 is 20-240 ng/mL. 2.Immobilized Anti-Tigit Antibody, Human IgG1 (Tiragolumab) at 2 μg/mL (100 μL/well) can bind Recombinant Human TIGIT Protein (ECD, His Tag) (Cat: 10917-H08H2), the EC50 is 0.5-1.5 ng/mL (Routinely tested) .

Function

Met1-Pro141

Molecular Weight

The recombinant human TIGIT consists of 131 amino acids and predicts a molecular mass of 14.5 kDa. As a result of glycosylation, it migrates as an approximately 19.7 KDa band in SDS-PAGE under reducing conditions.