THPO Protein (C-His, Human)

Product Specifications

Abbreviation

THPO

Synonyms

CAMT2, MGDF, MKCSF, ML, MPLLG, THC9, THCYT1, TPO

Host

HEK 293

Tag

C-His

Endotoxin

< 1.0 EU per μg protein as determined by the LAL method.

Purity

> 85 % as determined by SDS-PAGE

Bioactivity

1.Measured in a cell proliferation assay using MO7e human megakaryocytic leukemic cells. The ED50 for this effect is typically 0.15-1.5 ng/ml (QC tested) . 2.Recombinant Mouse C-MPL Protein (His Tag) (Cat: 5A7679-M08H1) immobilized on CM5 chip, can bind Recombinant Human Thrombopoietin / THPO Protein (His Tag) (Cat: 10381-H08H1) with an affinity constant of 14.900 nM as determined in an SPR assay (Biacore 8K) (Routinely tested) .