THPO Protein (C-His, Cynomolgus)

Product Specifications

Abbreviation

THPO

Host

HEK 293

Tag

C-His

Endotoxin

< 1.0 EU per μg of the protein as determined by the LAL method

Purity

> 86 % as determined by SDS-PAGE

Bioactivity

Measured in a cell proliferation assay using MO7e human megakaryocytic leukemic cells. The ED50 for this effect is typically 4-20 ng/mL.

Function

Met1-Gly353

Molecular Weight

The recombinant cynomolgus THPO consists of 343 amino acids and has a calculated molecular mass of 36.8 kDa. The apparent molecular mass of the recombinant protein is approximately 70-80 kDa in SDS-PAGE under reducing conditions due to glycosylation.