TGFBR1 Protein (C-human IgG1-Fc & His, Human)

1. Measured by its binding ability in a functional ELISA . Immobilized mouse CD105 at 10 μg/ml (100 μl/well) can bind human TGFRB1 with a linear range of 6.4-800 ng/ml . 2. Measured by its ability to bind human CD105 in a functional ELISA .

The recombinant human TGFBR1/Fc is a disulfide-linked homodimer. The reduced monomer consists of 340 amino acids and has a predicted molecular mass of 38.1 kDa. As a result of glycosylation, the apparent molecular mass of rh TGFBR1/Fc monomer is approximately 45-50 kDa in SDS-PAGE under reducing conditions, with ~10% free Fc fragments.