TF Protein (C-human IgG1-Fc, Mouse)
Product Specifications
Abbreviation
TF
Synonyms
Tf, Trf
Host
HEK 293
Tag
C-human IgG1-Fc
Endotoxin
< 1.0 EU per μg of the protein as determined by the LAL method
Purity
≥ 90 % as determined by SDS-PAGE. ≥ 90 % as determined by SEC-HPLC.
Bioactivity
Measured in a serum-free cell proliferation assay using MCF-7 human breast cancer cells. Karey, K.P. et al. (1988) Cancer Research 48:4083. The ED50 for this effect is typically 5-40 ng/mL.
Function
Met1-His697
Molecular Weight
The recombinant mouse TRF/Fc is a disulfide-linked homodimer. The reduced monomer comprises 919 amino acids and has a predicted molecular mass of 101.9 kDa. The apparent molecular mass of the protein is approximately 102 kDa in SDS-PAGE under reducing conditions due to glycosylation.
Species
Mouse
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