TEK Protein (C-human IgG1-Fc, Human)
Product Specifications
Abbreviation
TEK
Synonyms
CD202B, GLC3E, TIE-2, TIE2, VMCM, VMCM1
Host
HEK 293
Tag
C-human IgG1-Fc
Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
Purity
≥ 90 % as determined by SDS-PAGE. ≥ 90 % as determined by SEC-HPLC.
Bioactivity
1.Loaded Recombinant Human TIE-2 Protein, hFc Tag (Cat. No. 10700-H02H) on PROA Biosensor, can bind Recombinant Human Angiopoietin-2/ANGPT2 Protein, His Tag (Cat. No. 10691-H08H) with an affinity constant of 6.6 nM as determined in BLI assay (Sartorius Octet RED384) (QC tested) . 2.Loaded Recombinant Human TIE-2 Protein (hFc Tag) (Cat. No. 10700-H02H) on proA Biosensor, can bind Biotinylated Recombinant Human Angiopoietin-2/ANGPT2 Protein (His & AVI Tag) (Cat. No. 10691-H27H1-B) with an affinity constant of 0.547 μM as determined in BLI assay (Sartorius Octet RED384) (Routinely tested) .
Function
Met1-Lys745
Molecular Weight
The recombinant Human TEK consists of 961 amino acids and predicts a molecular mass of 107.37 kDa. As a result of glycosylation, the recombinant protein migrates as an approximately 132.5 kDa protein in SDS-PAGE under reducing conditions.
Species
Human
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