TEK Protein (C-human IgG1-Fc & His, Human)
Product Specifications
Abbreviation
TEK
Synonyms
CD202B, GLC3E, TIE-2, TIE2, VMCM, VMCM1
Host
HEK 293
Tag
C-human IgG1-Fc & His
Endotoxin
< 1.0 EU per μg of the protein as determined by the LAL method
Purity
≥ 90 % as determined by SDS-PAGE. ≥ 90 % as determined by SEC-HPLC.
Bioactivity
Measured by its binding ability in a functional ELISA. Immobilized recombinant human Angiopoietin-2 at 10 μg/ml (100 μl/well) can bind Human Tie2 / CD202b Protein (ECD, His & Fc Tag) with a range of 0.2-20 μg/ml.
Function
Met1-Lys745
Molecular Weight
The recombinant human Tie2/Fc is a disulfide-linked homodimeric protein. The reduced monomer consists of 970 amino acids and predicts a molecular mass of 108.5 kDa. As a result of glycosylation, the apparent molecular mass of rhTie2/Fc monomer is approximately 130.7 kDa in SDS-PAGE under reducing conditions.
Species
Human
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