TACSTD2 Protein (C-human IgG1-Fc, Human)

Product Specifications

Abbreviation

TACSTD2

Synonyms

EGP-1, EGP1, GA733-1, GA7331, GP50, M1S1, TROP2

Host

HEK 293

Tag

C-human IgG1-Fc

Endotoxin

< 1.0 EU per μg protein as determined by the LAL method.

Purity

≥ 95 % as determined by SDS-PAGE. ≥ 95 % as determined by SEC-HPLC.

Bioactivity

1.Immobilized Recombinant Human TROP2 Protein (ECD, Fc Tag) (Cat: 10428-H02H) at 2 μg/mL (100 μL/well) can bind biotinylated Anti-TROP2 Antibody, human IgG1, the EC50 is 0.4-3.0 ng/mL (QC tested) . 2.Anti-TROP2 (Research Grade Datopotamab Biosimilar) immobilized on CM5 chip, can bind Recombinant Human TROP2 Protein (ECD, Fc Tag) (Cat: 10428-H02H) with an affinity constant of 0.894 nM as determined in an SPR assay (Biacore 8K) (Routinely tested) .

Function

Met1-Thr274

Molecular Weight

The recombinant Human TACSTD2 consists of 486 amino acids and predicts a molecular mass of 54.6 kDa. It migrates as an approximately 67 kDa band in SDS-PAGE under reducing conditions.