TACSTD2 Protein (C-human IgG1-Fc & His, Human)

Product Specifications

Abbreviation

TACSTD2

Synonyms

EGP-1, EGP1, GA733-1, GA7331, GP50, M1S1, TROP2

Host

HEK 293

Tag

C-human IgG1-Fc & His

Endotoxin

< 1.0 EU per μg of the protein as determined by the LAL method

Purity

> 98 % as determined by SDS-PAGE

Bioactivity

Measured by the ability of the immobilized protein to support the adhesion of U937 human histiocytic lymphoma cells. When cells are added to coated plates (10μg/ml,100μl/well), approximately 55%-70% will adhere specifically.

Function

Met1-Thr274

Molecular Weight

The recombinant human TROP2/Fc is a disulfide-linked homodimer. The reduced monomer consists of 495 amino acids and has a predicted molecular mass of 55.7 kDa. In SDS-PAGE under reducing conditions, the apparent molecular mass of rhTROP2/Fc monomer is approximately 65-75 kDa due to glycosylation.