SOST Protein (N-AVI-his, Human)

Product Specifications

Abbreviation

SOST

Synonyms

CDD, DAND6, SOST1, UNQ2976/PRO7455/PRO7476, VBCH

Host

HEK 293

Tag

N-AVI-his

Endotoxin

< 1.0 EU per μg protein as determined by the LAL method.

Purity

≥ 95 % as determined by SDS-PAGE. ≥ 95 % as determined by SEC-HPLC.

Bioactivity

Immobilized Recombinant Human SOST/Sclerostin Protein (His & AVI Tag), Biotinylated (Cat: 10593-H44H1-B) at 2 μg/mL (100 μl/well) on streptavidin precoated (2 μg/mL, 100 μL/well) can bind Recombinant Human LRP6 Protein (Fc Tag) (Cat: 11968-H02H), the EC50 is 25-80 ng/mL (QC tested) .

Function

Gln24-Tyr213

Molecular Weight

The recombinant Human SOST comprises 245 amino acids and has a predicted molecular mass of 26.6 kDa. It migrates as approximately 37.1 kDa and 33.2 kDa band in SDS-PAGE under reducing conditions.