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SerpinE1 Protein (C-human IgG1-Fc, Rat)

Product Specifications

Abbreviation

SerpinE1

Synonyms

Pai1, PAI1A, Pai1aa, Planh, Planh1, RATPAI1A, Serpine1

Host

HEK 293

Tag

C-human IgG1-Fc

Endotoxin

< 1.0 EU per μg of the protein as determined by the LAL method

Purity

> 90 % as determined by SDS-PAGE

Bioactivity

Measured by its ability to inhibit uPA cleavage of a peptide substrate, N-carbobenzyloxy-Gly-Gly-Arg-7-amido-4-methylcoumarin (Z-GGR-AMC) . The IC50 value is < 10 nM.

Function

Met1-Pro402

Molecular Weight

The recombinant rat SERPINE1 comprises 620 amino acids and has a predicted molecular mass of 69.6 kDa. The apparent molecular mass of the protein is approximately 70 kDa in SDS-PAGE under reducing conditions.

Species

Rat

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