SerpinE1 Protein (C-His, Human)
Product Specifications
Abbreviation
SerpinE1
Synonyms
PAI, PAI-1, PAI1, PLANH1, SERPINE1
Host
HEK 293
Tag
C-His
Endotoxin
< 1.0 EU per μg of the protein as determined by the LAL method
Purity
≥ 97 % as determined by SDS-PAGE. ≥ 95 % as determined by SEC-HPLC.
Bioactivity
Measured by its ability to inhibit uPA cleavage of a peptide substrate, N-carbobenzyloxy-Gly-Gly-Arg-7-amido-4-methylcoumarin (Z-GGR-AMC) . The IC50 value is < 60 nM.
Function
Met1-Pro402
Molecular Weight
The mature recombinant human SerpinE1 consists of 390 amino acids and predicts a molecular mass of 44.2 kDa. In SDS-PAGE under reducing conditions, the apparent molecular mass of rhSerpinE1 is approximately 45 kDa.
Species
Human
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