SerpinA12 Protein (C-His, Human)

Product Specifications

Abbreviation

SerpinA12

Synonyms

OL-64, SERPINA12, Vaspin

Host

HEK 293

Tag

C-His

Endotoxin

< 1.0 EU per μg of the protein as determined by the LAL method

Purity

≥ 97 % as determined by SDS-PAGE. ≥ 90 % as determined by SEC-HPLC.

Bioactivity

Measured by its ability to inhibit KLK7 cleavage the fluorogenic peptide substrate, Mca-RPKPVE-Nval-WRK (Dnp) -NH2 (Catalog # ES002) . The IC50 is <75 nM.

Function

Met1-Lys414

Molecular Weight

The recombinant human SERPINA12 consists of 405 amino acids and predictes a molecular mass of 46.5 kDa. In SDS-PAGE under reducing conditions, the apparent molecular mass of rh SERPINA12 is approximately 50-55 kDa due to glycosylation.