SELL Protein (C-human IgG1-Fc & His, Mouse)

Product Specifications

Abbreviation

SELL

Synonyms

CD62L, L-selectin, LAM-1, LECAM-1, LECAM1, Lnhr, Ly-22, Ly-m22, Ly22, Lyam-1, Lyam1, Sell

Host

HEK 293

Tag

C-human IgG1-Fc & His

Endotoxin

< 1.0 EU per μg of the protein as determined by the LAL method

Purity

> 90 % as determined by SDS-PAGE

Bioactivity

Measured by the ability of the immobilized protein to support the adhesion of U937 human histiocytic lymphoma cells. When cells are added to SELL coated plates (10 μg/mL, 100 μL/well) approximately >60% cells will adhere specifically.

Function

Met1-Asn332

Molecular Weight

The recombinant mouse SELL/Fc is a disulfide-linked homodimer after removal of the signal peptide. The reduced monomer consists of 542 amino acids and has a predicted molecular mass of 61 kDa. In SDS-PAGE under reducing conditions, the apparent molecular mass of rm SELL/Fc monomer is approximately 100-110 kDa due to glycosylation.