RSPO2 Protein (C-human IgG1-Fc, Human)

Product Specifications

Abbreviation

RSPO2

Synonyms

CRISTIN2, HHRRD, MGC35555, TETAMS2, UNQ9384/PRO34209

Host

HEK 293

Tag

C-human IgG1-Fc

Endotoxin

< 1.0 EU per μg protein as determined by the LAL method.

Purity

> 90 % as determined by SDS-PAGE

Bioactivity

Measured by its ability to induce activation of ßcatenin response in a Topflash Luciferase assay using HEK293T human embryonic kidney cells. The ED50 for this effect is typically 2-12 ng/mL in the presence of 5 ng/mL recombinant mouse Wnt3a.

Function

Met1-Gly205

Molecular Weight

The recombinant human RSPO2 consists of 422 amino acids and predicts a molecular mass of 48.01 kDa. It migrates as an approximately 56.15 kDa band in SDS-PAGE under reducing conditions.