ROR1 Protein (C-human IgG1-Fc, Human)

Product Specifications

Abbreviation

ROR1

Synonyms

DJ537F10.1, NTRKR1

Host

HEK 293

Tag

C-human IgG1-Fc

Endotoxin

< 1.0 EU per μg of the protein as determined by the LAL method

Purity

> 90 % as determined by SDS-PAGE

Bioactivity

1.Immobilized Recombinant Human ROR1 Protein (Fc Tag) (Cat: 13968-H02H1) at 2 μg/mL (100 μL/well) can bind Anti-ROR1 Antibody, human IgG1, the EC50 is 7.5-22.5 ng/mL. 2.Loaded Zilovertamab on AR2G Biosensor, can bind Recombinant Human ROR1 Protein, hFc Tag (Cat. No. 13968-H02H1) with an affinity constant of 0.929 nM as determined in BLI assay (Sartorius Octet RED384) (Routinely tested) .

Function

Met1-Glu403

Molecular Weight

The recombinant human ROR1/Fc comprises 615 amino acids and has a predicted molecular mass of 69 kDa. The apparent molecular mass of the protein is approximately 69 kDa in SDS-PAGE under reducing conditions.