PTPN2 Protein (N-GST & His, Human)

Product Specifications

Abbreviation

PTPN2

Synonyms

PTN2, PTPT, TC-PTP, TC45, TC48, TCELLPTP, TCPTP

Host

Baculovirus-insect Cells

Tag

N-GST & His

Endotoxin

< 1.0 EU per μg of the protein as determined by the LAL method

Purity

> 90 % as determined by SDS-PAGE

Bioactivity

Measured by its ability to dephosphorylate a phosphotyrosine residue in an EGF receptor 988-998 phosphopeptide substrate, R&D Systems, Catalog # ES006. The specific activity is > 20 nmoles/min/μg.

Function

Met1-Asn314

Molecular Weight

The recombinant human PTPN2 (aa 1-314) /GST chimera consists of 551 amino acids and predicts a molecular mass of 64.4 kDa. It migrates as an approximately 60 kDa band in SDS-PAGE under reducing conditions.