PTPN2 Protein (N-cleavage, Human)

Product Specifications

Abbreviation

PTPN2

Synonyms

PTN2, PTPT, TC-PTP, TC45, TC48, TCELLPTP, TCPTP

Host

Baculovirus-insect Cells

Tag

N-cleavage

Endotoxin

< 1.0 EU per μg of the protein as determined by the LAL method

Purity

> 95 % as determined by SDS-PAGE

Bioactivity

Measured by its ability to dephosphorylate a phosphotyrosine residue in an EGF receptor 988-998 phosphopeptide substrate, R&D Systems, Catalog # ES006. The specific activity is > 30 μmoles/min/mg.

Function

Met1-Asn314

Molecular Weight

The secreted recombinant human PTPN2 consists of 316 amino acids and predicts a molecular mass of 36.8 KDa. The apparent molecular mass of the protein is approximately 37 KDa in SDS-PAGE under reducing conditions due to glycosylation.