PTPN11 Protein (C-His, Mouse)

Product Specifications

Abbreviation

PTPN11

Synonyms

2700084A17Rik, PTP1D, PTP2C, Ptpn11, SAP-2, SH-PTP2, SH-PTP3, SHP-2, Shp2, Syp

Host

HEK 293

Tag

C-His

Endotoxin

< 1.0 EU per μg of the protein as determined by the LAL method

Purity

> 90 % as determined by SDS-PAGE

Bioactivity

Measured by its ability to dephosphorylate a tyrosine residue in a peptide containing the EGFR Y992 phosphorylation site (Catalog # ES006) . The specific activity is > 1 pmoles/min/μg.

Function

Met1-Arg593

Molecular Weight

The recombinant mouse PTPN11 comprises 604 amino acids and has a predicted molecular mass of 69.5 kDa. The apparent molecular mass of the protein is approximately 65 kDa in SDS-PAGE under reducing conditions due to glycosylation.