PDGFRA Protein (C-human IgG1-Fc, Human)

Product Specifications

Abbreviation

PDGFRA

Synonyms

CD140A, GAS9, PDGFR-2, PDGFR2, RHEPDGFRA

Host

HEK 293

Tag

C-human IgG1-Fc

Endotoxin

< 1.0 EU per μg of the protein as determined by the LAL method

Purity

≥ 90 % as determined by SDS-PAGE. ≥ 85 % as determined by SEC-HPLC.

Bioactivity

Measured by its ability to bind human PDGFC-His a functional ELISA.

Function

Met1-Glu524

Molecular Weight

The recombinant human PDGFRα/Fc is a disulfide-linked homodimeric protein after removal of the signal peptide. The reduced monomer consists of 739 amino acids and predicts a molecular mass of 82.9 kDa. By SDS-PAGE under reducing conditions, the apparent molecular mass of rhPDGFRα/Fc is approximately 120-130 kDa due to the glycosylation.