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PDCD1LG2 Protein (C-human IgG1-Fc, Human)

Product Specifications

Abbreviation

PDCD1LG2

Synonyms

B7-DC, B7DC, bA574F11.2, Btdc, CD273, PD-L2, PDCD1L2, PDL2

Host

HEK 293

Tag

C-human IgG1-Fc

Endotoxin

< 1.0 EU per μg protein as determined by the LAL method.

Purity

≥ 95 % as determined by SDS-PAGE. ≥ 90 % as determined by SEC-HPLC.

Bioactivity

1. Measured by its binding ability in a functional ELISA. 2. Immobilized human PD1-His (Cat:10377-H08H) at 10 μg/mL (100 μL/well) can bind human PDCD1LG2-Fc. The EC50 of PDCD1LG2-Fc is 0.05-0.12 μg/mL. 3.Loaded Recombinant Human PD-L2/B7-DC Protein, hFc Tag (Cat. No. 10292-H02H) on proA Biosensor, can bind Recombinant Human PD-1 Protein, His Tag (Cat. No. 10377-H08H) with an affinity constant of 0.435 μM as determined in BLI assay (Sartorius Octet RED384) (Routinely tested) . 4.Loaded Recombinant Human PD-1 Protein, His Tag (Cat. No. 10377-H08H) on HIS1K Biosensor, can bind Recombinant Human PD-L2/B7-DC Protein, hFc Tag (Cat. No. 10292-H02H) with an affinity constant of 19.400 nM as determined in BLI assay (Sartorius Octet RED384) (Routinely tested) .

Function

Met1-Pro219

Molecular Weight

The recombinant human PDCD1LG2 consists 438 amino acids and predicts a molecular mass of 49.3 kDa.

Species

Human

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