PDCD1 Protein (C-human IgG1-Fc, Canine)

Product Specifications

Abbreviation

PDCD1

Host

HEK 293

Tag

C-human IgG1-Fc

Endotoxin

< 1.0 EU per μg protein as determined by the LAL method.

Purity

≥ 95 % as determined by SDS-PAGE. ≥ 95 % as determined by SEC-HPLC.

Bioactivity

1.Immobilized PD-1 Protein, Canine, Recombinant (hFc Tag) (Cat:70109-D02H) at 2 μg/mL (100 μL/well) can bind PD-L1 Protein, Canine, Recombinant (hFc Tag), Biotinylated (Cat:70110-D02H-B), the EC50 is 300-1200 ng/mL. (Routinely tested) 2. Loaded Recombinant Canine PD-L1/B7-H1 Protein, His Tag (Cat. No. 70110-D08H) on NTA Biosensor, can bind Recombinant Canine PD-1 Protein, hFc Tag (Cat. No. 70109-D02H) with an affinity constant of 44.1 nM as determined in BLI assay (Sartorius Octet RED384) (QC tested) .

Function

Met1-Leu169

Molecular Weight

The recombinant canine PDCD1 consists 383 amino acids and predicts a molecular mass of 43 kDa.

Species

Canine