PDCD1 Protein (C-human IgG1-Fc & His, Human)
Product Specifications
Abbreviation
PDCD1
Synonyms
CD279, hPD-1, hPD-l, hSLE1, PD-1, PD1, SLEB2
Host
HEK 293
Tag
C-human IgG1-Fc & His
Endotoxin
< 1.0 EU per μg of the protein as determined by the LAL method
Purity
≥ 97 % as determined by SDS-PAGE. ≥ 85 % as determined by SEC-HPLC.
Bioactivity
1.Immobilized Anti-PD1 (Research grade Nivolumab biosimilar) at 2 μg/mL (100 μL/well) can bind Recombinant Human PD1 / PDCD1 Protein (His & Fc Tag) (Cat: 10377-H03H), the EC50 is 1-4 ng/mL (QC tested) . 2.Immobilized Recombinant Human PD1 / PDCD1 Protein (His & Fc Tag) (Cat: 10377-H03H) at 2 μg/mL (100 μL/well) can bind Recombinant Human PD-L2 Protein (Fc & AVI Tag), Biotinylated (Cat: 10292-H41H-B), the EC50 is 2.1 ng/mL (Routinely tested) .
Function
Met1-Gln167
Molecular Weight
The recombinant human PD1/Fc is a disulfide-linked homodimeric protein. The reduced monomer consists of 390 amino acids and has a calculated molecular mass of 43.84 kDa. As a result of glycosylation, human PD1/Fc monomer migrates as an approximately 55-66 kDa protein in SDS-PAGE under reducing conditions.
Species
Human
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