PCSK9 Protein (C-His, Mouse)

Product Specifications

Abbreviation

PCSK9

Synonyms

FH3, HCHOLA3, Narc1, PC9, Pcsk9

Host

HEK 293

Tag

C-His

Endotoxin

< 1.0 EU per μg of the protein as determined by the LAL method

Purity

≥ 95 % as determined by SDS-PAGE. ≥ 90 % as determined by SEC-HPLC.

Bioactivity

Immobilized Recombinant Human LDL Receptor Protein (Fc Tag) (Cat: 10231-H05H) at 2 μg/mL (100 μL/well) can bind Recombinant Mouse PCSK9 / NARC1 Protein (His Tag) (Cat: 50251-M08H), the EC50 is 40-120 ng/mL.

Function

Met1-Gln694

Molecular Weight

The secreted recombinant mouse PCSK9 consists of 671 amino acids and has a calculated molecular mass of 72.6 kDa. As a result of proteolysis and glycosylation, the recombinant protein migrates as doublet with apparent molecular mass of approximately 19 & 65 kDa, cprresponding to the prodomain and the mature form of PCSK9 respectively in SDS-PAGE under reducing conditions.