PCSK9 Protein (C-His, Rat)

Product Specifications

Abbreviation

PCSK9

Synonyms

NARC-1, Narc1, PC9, Pcsk9

Host

HEK 293

Tag

C-His

Endotoxin

< 1.0 EU per μg of the protein as determined by the LAL method

Purity

> 97 % as determined by SDS-PAGE

Bioactivity

Immobilized Recombinant Human LDLR/LDL Receptor Protein (mFc Tag) (Cat: 10231-H05H) at 2 μg/mL (100 μL/well) can bind Recombinant Rat PCSK9 / NARC1 Protein (His Tag) (Cat: 80005-R08H), the EC50 is 70-210 ng/mL (QC tested) .

Function

Met1-Gln691

Molecular Weight

The secreted recombinant pro form of rat PCSK9 comprises 672 amino acids and predicts a molecular mass of 72.8 kDa. As a result of glycosylation and proteolytic digestion, rat PCSK9 migrates as doublet with apparent molecular mass of 20 kDa and 62 kDa corresponding to the pro domain and mature form respectively in SDS-PAGE under reducing conditions.