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OSMR Protein (C-His, Human)

Product Specifications

Abbreviation

OSMR

Synonyms

IL-31R-beta, IL-31RB, OSMRB, OSMRbeta, PLCA1

Host

HEK 293

Tag

C-His

Endotoxin

< 1.0 EU per μg of the protein as determined by the LAL method

Purity

≥ 96 % as determined by SDS-PAGE. ≥ 90 % as determined by SEC-HPLC.

Bioactivity

1.Loaded Anti-Human OSMR antibody, human IgG1 on ProA Biosensor, can bind Recombinant Human OSMR Protein, His Tag (Cat. No. 11226-H08H) with an affinity constant of 0.40 nM as determined in a BLI assay (Sartorius Octet Red384) (Routinely tested) . 2.Immobilized Anti-OSMRβ Antibody at 2 μg/mL (100 μL/well) can bind Recombinant Human OSMR / IL31RB Protein (His Tag) (Cat:11226-H08H), The EC50 is 4-12 ng/mL.

Function

Met1-Met740

Molecular Weight

The secreted recombinant human OSMR comprises 724 amino acids and has a predicted molecular mass of 82.6 kDa. As a result of glycosylation, rh OSMR migrates as an approximately 130-140 kDa band in SDS-PAGE under reducing conditions.