OSMR Protein (C-His, Human)

Product Specifications

Abbreviation

OSMR

Synonyms

IL-31R-beta, IL-31RB, OSMRB, OSMRbeta, PLCA1

Host

HEK 293

Tag

C-His

Endotoxin

< 0.5 EU per mg protein.

Purity

≥ 90 % as determined by SDS-PAGE. ≥ 85 % as determined by SEC-HPLC. ≥ 85 % as determined by SEC-MALS (Routinely tested) .

Bioactivity

1.Immobilized Anti-OSMRβ (Research Grade Vixarelimab Biosimilar) at 2 μg/mL (100 μL/well) can bind Recombinant Human OSMR / IL31RB Protein (His Tag) (Cat: 11226-H08H-UE), the EC50 is 3-9 ng/mL (Routinely tested) . 2.Loaded Anti-OSMRβ (Research Grade Vixarelimab Biosimilar) on proA Biosensor, can bind Recombinant Human OSMR / IL31RB Protein (His Tag) (Cat. No. 11226-H08H-UE) with an affinity constant of 0.668 nM as determined in BLI assay (Sartorius Octet RED384) (Routinely tested) .

Function

Met 1-Met 740

Molecular Weight

The secreted recombinant human OSMR comprises 724 amino acids and has a predicted molecular mass of 82.6 kDa. As a result of glycosylation, the band migrates approximately 120-150 kDa in the SDS-PAGE under reducing conditions. The molecular weight of this protein is around 122.9 kDa verified by SEC-MALS (Routinely tested) .