NTRK3 Protein (C-human IgG1-Fc & His, Human)

1.Immobilized human TrKc-Fch at 10 μg/ml (100 μl/well) can bind biotinylated human NT3 (Cat:10286-HNAE), The EC50 of biotinylated human NT3 (Cat:10286-HNAE) is 23.4-54.6 ng/ml. 2.Loaded Recombinant Human TrkC Protein, His & hFc Tag (Cat. No. 10048-H03H) on ProA Biosensor, can bind Recombinant Human PTPRS Protein, His Tag (Cat. No. 30137-H08H) with an affinity constant of 14 nM as determined in BLI assay (Sartorius Octet RED384) (Routinely tested) .

The recombinant human TrkC/Fc is a disulfide-linked homodimeric protein after removal of the signal peptide. It consists of 644 amino acids and has a calculated molecular mass of 72.5 kDa. As a result of glycosylation, rh TrkC/Fc monomer migrates as an approximately 110-120 kDa protein in SDS-PAGE under reducing conditions.