NTRK1 Protein (N-human IgG1-Fc, Canine)
Product Specifications
Abbreviation
NTRK1
Host
HEK 293
Tag
N-human IgG1-Fc
Endotoxin
< 1.0 EU per μg of the protein as determined by the LAL method
Purity
> 90 % as determined by SDS-PAGE
Bioactivity
Measured by its ability to inhibit NGF-induced proliferation of TF‐1 human erythroleukemic cells. The ED50 for this effect is typically 2-8 μg/mL in the presence of 10 ng/mL of recombinant human NGF.
Function
Pro285-Lys410
Molecular Weight
The recombinant canine NTRK1/Fc is a disulfide-linked homodimer. The reduced monomer comprises 386 amino acids and has a predicted molecular mass of 42.3 kDa. The apparent molecular mass of the protein is approximately 55-61 kDa in SDS-PAGE under reducing conditions.
Species
Canine
Frequently Asked Questions
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