NTRK1 Protein (N-His, Human)

Product Specifications

Abbreviation

NTRK1

Synonyms

MTC, p140-TrkA, TRK, Trk-A, TRK1, TRKA

Host

E. coli

Tag

N-His

Purity

> 97 % as determined by SDS-PAGE

Bioactivity

Measured by its ability to inhibit NGF-induced proliferation of TF-1 human erythroleukemic cells. The ED50 for this effect is typically 0.2-0.8 μg/ml in the presence of 10 ng/mL of Recombinant human NGF.

Function

Pro285-Glu413

Molecular Weight

The recombinant human NTRK1 Ig-like C2-type 2 domain (aa 285-413) consists of 136 amino acids and has a predicted molecular mass of 15.1 kDa. It migrates as an approximately 16 kDa band in SDS-PAGE under reducing conditions.