NTRK1 Protein (C-human IgG1-Fc, Rat)

Product Specifications

Abbreviation

NTRK1

Synonyms

Ntrk1, Trk, Trka

Host

HEK 293

Tag

C-human IgG1-Fc

Endotoxin

< 1.0 EU per μg of the protein as determined by the LAL method

Purity

> 95 % as determined by SDS-PAGE

Bioactivity

Measured by its ability to inhibit NGF-induced proliferation of TF‐1 human erythroleukemic cells. The ED50 for this effect is typically 0.01-0.1 μg/mL in the presence of 10 ng/mL of recombinant mouse NGF.

Function

Met1-Pro418

Molecular Weight

The recombinant rat NTRK1/Fc is a disulfide-linked homodimer. The reduced monomer comprises 627 amino acids and has a predicted molecular mass of 69.2 kDa. The apparent molecular mass of the protein is approximately 92-102 kDa in SDS-PAGE under reducing conditions.