NTRK1 Protein (C-human IgG1-Fc, Mouse)
Product Specifications
Abbreviation
NTRK1
Synonyms
Ntrk1, Tkr, trk, TrkA
Host
HEK 293
Tag
C-human IgG1-Fc
Endotoxin
< 1.0 EU per μg of the protein as determined by the LAL method
Purity
> 90 % as determined by SDS-PAGE
Bioactivity
Measured by its ability to inhibit NGF-induced proliferation of TF‐1 human erythroleukemic cells. The ED50 for this effect is typically 0.02-0.08 μg/mL in the presence of 10 ng/mL of recombinant mouse NGF.
Function
Met1-Gly420
Molecular Weight
The recombinant mouse NTRK1 /Fc is a disulfide-linked homodimer. The reduced monomer comprises 628 amino acids and has a predicted molecular mass of 69.2 kDa. The apparent molecular mass of the protein is approximately 116 kDa in SDS-PAGE under reducing conditions due to glycosylation.
Species
Mouse
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