NTRK1 Protein (C-human IgG1-Fc, Mouse)

Product Specifications

Abbreviation

NTRK1

Synonyms

Ntrk1, Tkr, trk, TrkA

Host

HEK 293

Tag

C-human IgG1-Fc

Endotoxin

< 1.0 EU per μg of the protein as determined by the LAL method

Purity

> 90 % as determined by SDS-PAGE

Bioactivity

Measured by its ability to inhibit NGF-induced proliferation of TF‐1 human erythroleukemic cells. The ED50 for this effect is typically 0.02-0.08 μg/mL in the presence of 10 ng/mL of recombinant mouse NGF.

Function

Met1-Gly420

Molecular Weight

The recombinant mouse NTRK1 /Fc is a disulfide-linked homodimer. The reduced monomer comprises 628 amino acids and has a predicted molecular mass of 69.2 kDa. The apparent molecular mass of the protein is approximately 116 kDa in SDS-PAGE under reducing conditions due to glycosylation.