NRG1 Protein (N-mouse IgG1-Fc, Human)

Product Specifications

Abbreviation

NRG1

Synonyms

ARIA, GGF, GGF2, HGL, HRG, HRG1, HRGA, MST131, MSTP131, NDF, NRG1-IT2, SMDF

Host

HEK 293

Tag

N-mouse IgG1-Fc

Endotoxin

< 1.0 EU per μg of the protein as determined by the LAL method

Purity

> 88 % as determined by SDS-PAGE

Bioactivity

1. Measured by its ability to bind with human ErbB4-His (Cat:10363-H08H) in a functional ELISA. 2. Measured by its ability to bind with human ErbB3-His (Cat:10201-H08H) in a functional ELISA.

Function

Ser2-Lys246

Molecular Weight

The recombinant human NRG1/mFc is a disulfide-linked homodimer. The reduced monomer comprises 481 amino acids and has a predicted molecular mass of 53.4 kDa. The apparent molecular mass of the monomer is approximately 67 kDa in SDS-PAGE under reducing conditions due to glycosylation.