NRG1 Protein (C-human IgG1-Fc, Human)
Product Specifications
Abbreviation
NRG1
Synonyms
ARIA, GGF, GGF2, HGL, HRG, HRG1, HRGA, MST131, MSTP131, NDF, NRG1-IT2, SMDF
Host
HEK 293
Tag
C-human IgG1-Fc
Endotoxin
< 1.0 EU per μg of the protein as determined by the LAL method
Purity
> 87 % as determined by SDS-PAGE
Bioactivity
1. Measured by its ability to biotinylated Human ErbB4-Fc (cat:10363-H03H) in functional Elisa. 2. Measured by its ability to biotinylated Rhesus ErbB3-His (Cat:90043-K08H) in functional Elisa. 3. Measured by its ability to biotinylated Rhesus ErbB3 (Cat:90043-K02H) in functional Elisa.
Function
Ser20-Lys241
Molecular Weight
The recombinant human NRG1/Fc chimera is a disulfide-linked homodimeric protein. The reduced monomer consists of 463 amino acids and has a calculated molecular mass of 51 kDa. In SDS-PAGE under reducing conditions, the apparent molecular mass of rh NRG1/Fc monomer is approximately 60 kDa.
Species
Human
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