What is the catalog number for NOG Protein (C-human IgG1-Fc, Mouse)?

The catalog number for NOG Protein (C-human IgG1-Fc, Mouse) is P527109.

What sizes are available for NOG Protein (C-human IgG1-Fc, Mouse)?

NOG Protein (C-human IgG1-Fc, Mouse) is available in the following size(s): 100 µg.

Is NOG Protein (C-human IgG1-Fc, Mouse) in stock?

NOG Protein (C-human IgG1-Fc, Mouse) is currently made to order / not held in immediate stock. Contact us for lead time.

Does this cell line or biologic require a Material Transfer Agreement (MTA)?

Some products, including certain cell lines, plasmids, and tissue cultures, are subject to intellectual property terms and may require an MTA before we can ship. We’ll inform you in advance if this product requires one, and additional handling fees may apply.

What should I do if I need to report a performance issue with a specific lot of this product?

Provide the catalogue number, product name, lot number, and your experimental results to our technical support team. They’ll investigate and, if needed, escalate to the manufacturer, provided the product was used before expiry and stored correctly.

What is the isotype of this antibody?

Isotype information such as IgG1 or IgG2a is listed in the product specifications on the datasheet, relevant for selecting compatible detection reagents.

NOG Protein (C-human IgG1-Fc, Mouse)

Abbreviation

NOG

Synonyms

Nog

Host

HEK 293

Tag

C-human IgG1-Fc

Endotoxin

< 1.0 EU per μg of the protein as determined by the LAL method

Purity

> 85 % as determined by SDS-PAGE

Bioactivity

1.Measured by its ability to inhibit BMP4-induced alkaline phosphatase production by MC3T3-E1 cells. The ED50 for this effect is typically 0.1-0.6μg/mL. 2.Human intestinal cancer organoids were cultured with RSPO1 (Cat#11083-HNAS), EGF (Cat#50482-MNCH), NOG (Cat#50688-M02H) . (Routinely tested) . Data provided by D1 Medical Technology. 3.Human colorectum organoids were cultured with RSPO1 (Cat#11083-HNAS), EGF (Cat#50482-MNCH), NOG (Cat#50688-M02H) . (Routinely tested) . Data provided by D1 Medical Technology. 4.Human lung cancer organoids were cultured with FGF2 (Cat#10014-HNAE), FGF4 (Cat#16043-HNAE), FGF7 (Cat#10210-H07E), EGF (Cat#50482-MNCH), FGF10 (Cat#10573-HNAE), NOG (Cat#50688-M02H), RSPO1 (Cat#11083-HNAS) . (Routinely tested) . Data provided by D1 Medical Technology. 5.Human lung organoids were cultured with FGF2 (Cat#10014-HNAE), FGF4 (Cat#16043-HNAE), FGF7 (Cat#10210-H07E), EGF (Cat#50482-MNCH), FGF10 (Cat#10573-HNAE), NOG (Cat#50688-M02H), RSPO1 (Cat#11083-HNAS) . (Routinely tested) . Data provided by D1 Medical Technology. 6.Human cholangiocarcinomas organoids were cultured with FGF2 (Cat#10014-HNAE), HGF (Cat#10463-HNAS), FGF7 (Cat#10210-H07E), EGF (Cat#50482-MNCH), FGF10 (Cat#10573-HNAE), NOG (Cat#50688-M02H), RSPO1 (Cat#11083-HNAS) . (Routinely tested) . Data provided by D1 Medical Technology. 7.Human liver cancer organoids were cultured with FGF2 (Cat#10014-HNAE), HGF (Cat#10463-HNAS), FGF7 (Cat#10210-H07E), EGF (Cat#50482-MNCH), FGF10 (Cat#10573-HNAE), TGFB1 (Cat#10804-HNAC), NOG (Cat#50688-M02H), RSPO1 (Cat#11083-HNAS) . (Routinely tested) . Data provided by D1 Medical Technology. 8.Human kidney cancer organoids were cultured with FGF2 (Cat#10014-HNAE), FGF7 (Cat#10210-H07E), EGF (Cat#50482-MNCH), FGF10 (Cat#10573-HNAE), NOG (Cat#50688-M02H), RSPO1 (Cat#11083-HNAS) . (Routinely tested) . Data provided by D1 Medical Technology. 9.Human kidney organoids were cultured with FGF7 (Cat#10210-H07E), EGF (Cat#50482-MNCH), FGF10 (Cat#10573-HNAE), NOG (Cat#50688-M02H), RSPO1 (Cat#11083-HNAS), HGF (Cat#10463-HNAS), FGF4 (Cat#16043-HNAE) . (Routinely tested) . Data provided by D1 Medical Technology. 10.Human gastric cancer organoids were cultured with EGF (Cat#50482-MNCH), FGF10 (Cat#10573-HNAE), NOG (Cat#50688-M02H), RSPO1 (Cat#11083-HNAS) . (Routinely tested) . Data provided by D1 Medical Technology. 11.Human stomach organoids organoids were cultured with EGF (Cat#50482-MNCH), FGF10 (Cat#10573-HNAE), NOG (Cat#50688-M02H), RSPO1 (Cat#11083-HNAS) . (Routinely tested) . Data provided by D1 Medical Technology. 12.Human breast cancer organoids were cultured with FGF7 (Cat#10210-H07E), RSPO1 (Cat#11083-HNAS), IGF1 (Cat#10598-HNAE), EGF (Cat#50482-MNCH), NRG1 Beta 1 (Cat#11609-H01H), NOG (Cat#50688-M02H) . (Routinely tested) . Data provided by D1 Medical Technology. 13.Human ovarian organoids were cultured with IGF1 (Cat#10598-HNAE), NRG1 Beta 1 (Cat#11609-H01H), RSPO1 (Cat#11083-HNAS), EGF (Cat#50482-MNCH), NOG (Cat#50688-M02H) . (Routinely tested) . Data provided by D1 Medical Technology. 14.Human small intestinal organoids were cultured with IL22 (Cat#13059-HNAE), FGF10 (Cat#10573-HNAE), EGF (Cat#50482-MNCH), NOG (Cat#50688-M02H) . (Routinely tested) . Data provided by D1 Medical Technology.

Function

Met1-Cys232

Molecular Weight

The recombinant mouse NOG/Fc comprises 454 amino acids and has a predicted molecular mass of 51 kDa. It migrates as approximately 60 kDa band in SDS-PAGE under reducing conditions.