NOG Protein (C-His, Human)
Product Specifications
Abbreviation
NOG
Synonyms
SYM1, SYNS1, SYNS1A
Host
HEK 293
Tag
C-His
Endotoxin
< 1.0 EU per μg of the protein as determined by the LAL method
Purity
> 95 % as determined by SDS-PAGE
Bioactivity
Measured by its ability to inhibit recombinant human BMP4-induced alkaline phosphatase production by MC3T3-E1 cells. The ED50 for this effect is typically 10-60 ng/mL in the presence of 25 ng/mL of recombinant human BMP4.
Function
Met1-Cys232
Molecular Weight
The recombinant human Noggin comprises 216 amino acids after removal of the signal peptide and has a predicted molecular mass of 24.6 kDa. As a result of glycosylation, rhNoggin migrates as an approximately 30 kDa bnd in SDS-PAGE under reducing conditions.
Species
Human
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