Triclocarban-d4

Triclocarban-d4 is the deuterium labeled Triclocarban. Triclocarban (3,4,4′-Trichlorocarbanilide), a broad spectrum antibacterial compound, is widely used in a broad range of applications such as the production of soaps, skin creams, toothpastes and deodorants. Triclocarban is a potential endocrine-disrupting chemical with the capacity to modulate androgen and estrogen activities as well as other hormone-mediated biological processes[1][2][3].

Product Specifications

CAS Number

[1219799-29-7]

Product Name Alternative

3,4,4′-Trichlorocarbanilide-d4

UNSPSC

12352005

Target

Bacterial

Type

Isotope-Labeled Compounds

Related Pathways

Anti-infection

Field of Research

Infection

Purity

98.0

Solubility

DMSO : 100mg/mL (ultrasonic)

Smiles

ClC(C([2H])=C1[2H])=C([2H])C([2H])=C1NC(NC2=CC(Cl)=C(C=C2)Cl)=O

Molecular Formula

C13H5D4Cl3N2O

Molecular Weight

319.61

References & Citations

[1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53 (2) :211-216. |[2]Kanbara Y, et al. Nanomolar concentration of triclocarban increases the vulnerability of rat thymocytes to oxidative stress. J Toxicol Sci. 2013 Feb;38 (1) :49-55.|[3]Huang H, et al. The in vitro estrogenic activities of triclosan and triclocarban. J Appl Toxicol. 2014 Sep;34 (9) :1060-7.|[4]Kennedy RC, et al. Early life triclocarban exposure during lactation affects neonate rat survival. Reprod Sci. 2015 Jan;22 (1) :75-89.