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MS4A1 Protein (N-Strep & C-His, Human)

Product Specifications

Abbreviation

MS4A1

Synonyms

B1, Bp35, CD20, CVID5, FMC7, LEU-16, S7

Host

HEK 293

Tag

N-Strep & C-His

Endotoxin

< 1.0 EU per μg protein as determined by the LAL method.

Purity

≥ 75 % as determined by SDS-PAGE.

Bioactivity

1.Immobilized Obinutuzumab derived Anti-CD20 antibody, Human IgG1 at 2 μg/mL (100 μL/well) can bind Recombinant Human CD20-Nanodisc (Full Length) Protein (Cat: 11007-H93H-NB), the EC50 is 1-5 ng/mL. 2.Immobilized Rituximab derived Anti-CD20 antibody, Human IgG1 at 2 μg/mL (100 μL/well) can bind Recombinant Human CD20-Nanodisc (Full Length) Protein (Cat: 11007-H93H-NB), the EC50 is 2-8 ng/mL. 3.Immobilized Recombinant Human CD20 Protein (Nanodisc, Full-length, Strep & His Tag) (Cat: 11007-H93H-NB) at 5 μg/mL (100 μL/well) can bind Obinutuzumab derived Anti-CD20 antibody, Human IgG1, the EC50 is 4.0-12.0 ng/mL (Routinely tested) . 4.Loaded Obinutuzumab on proA Biosensor, can bind Recombinant Human CD20 Protein, Nanodisc, Full-length, Strep & His Tag (Cat. No. 11007-H93H-NB) with an affinity constant of 11.000 nM as determined in BLI assay (Sartorius Octet RED384) (Routinely tested) . 5.Loaded Rituximab on proA Biosensor, can bind Recombinant Human CD20 Protein, Nanodisc, Full-length, Strep & His Tag (Cat. No. 11007-H93H-NB) with an affinity constant of 14.800 nM as determined in BLI assay (Sartorius Octet RED384) (Routinely tested) .

Function

Met1-Pro297

Molecular Weight

The recombinant Human MS4A1 consists of 333 amino acids and predicts a molecular mass of 36.71 kDa. It migrates as an approximately 41 kDa band in SDS-PAGE under reducing conditions.

Species

Human

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