MS4A1 Protein (Native, Human)
Product Specifications
Abbreviation
MS4A1
Synonyms
B1, Bp35, CD20, CVID5, FMC7, LEU-16, S7
Host
HEK 293
Tag
Native
Endotoxin
< 1.0 EU per μg of the protein as determined by the LAL method
Bioactivity
1.Immobilized Recombinant Human CD20 (Full Length) Protein-VLP (Cat: 11007-HNAH) at 5 μg/mL (100 μL/well) can bind Obinutuzumab, the EC50 is 1.0-3.0 ng/mL. (Routinely tested) 2.Immobilized Recombinant Human CD20 (Full Length) Protein-VLP (Cat: 11007-HNAH) at 5 μg/mL (100 μL/well) can bind Ofatumumab, the EC50 is 1.4-9.4 ng/ mL. (QC tested) 3.Immobilized Recombinant Human CD20 (Full Length) Protein-VLP (Cat: 11007-HNAH) at 5 μg/mL (100 μL/well) can bind Rituximab, the EC50 is 6-18 ng/mL. (QC tested) 4.Immobilized Recombinant Human CD20 (Full Length) Protein-VLP from competitor A and SINO at 5 μg/mL (100 μL/well) can bind anti-CD20 (Research grade Obinutuzumab biosimilar), the EC50 is 3 ng/mL and 1.7 ng/mL, respectively. The results demonstrated that SINO CD20 (Cat. No. 11007-HNAH) has a higher binding capacity than that of competitor A (Routinely tested) . 5.Immobilized Recombinant Human CD20 (Full Length) Protein-VLP from competitor A and SINO at 5 μg/mL (100 μL/well) can bind anti-CD20 (Research grade Ofatumumab biosimilar), the EC50 is 10.3 ng/mL and 5.4 ng/mL, respectively. The results demonstrated that SINO CD20 (Cat. No. 11007-HNAH) has a higher binding capacity than that of competitor A (Routinely tested) . 5.Immobilized Recombinant Human CD20 (Full Length) Protein-VLP from competitor A and SINO at 5 μg/mL (100 μL/well) can bind anti-CD20 (Research grade Rituximab biosimilar), the EC50 is 19.8 ng/mL and 34.9 ng/mL, respectively. The results demonstrated that SINO CD20 (Cat. No. 11007-HNAH) has a higher binding capacity than that of competitor A (Routinely tested) .
Function
Met1-Pro297
Molecular Weight
The recombinant human CD20 predicts a molecular mass of 33.08 kDa.
Species
Human
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