MPL Protein (C-His, Human)
Product Specifications
Abbreviation
MPL
Synonyms
C-MPL, CD110, MPLV, THCYT2, THPOR, TPOR
Host
HEK 293
Tag
C-His
Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
Purity
≥ 95 % as determined by SDS-PAGE. ≥ 90 % as determined by SEC-HPLC.
Bioactivity
1. Recombinant Human TPO/Thrombopoietin Protein, hFc Tag (Cat. No. 10381-H02H) captured on Protein A chip can bind Recombinant Human TPO-R Protein, His Tag (Cat. No. 10443-H08H) with an affinity constant of 12.3 nM as determined in an SPR assay (Biacore 8K) (Routinely tested) . 2. Loaded Recombinant Human TPO/Thrombopoietin Protein, hFc Tag (Cat. No. 10381-H02H) on ProA Biosensor, can bind Recombinant Human TPO-R Protein, His Tag (Cat. No. 10443-H08H) with an affinity constant of 9.06 nM as determined in BLI assay (Sartorius Octet RED384) (Routinely tested) .
Function
Met1-Trp491
Molecular Weight
The recombinant Human MPL consists of 477 amino acids and predicts a molecular mass of 54 kDa. It migrates as an approximately 68 kDa band in SDS-PAGE under reducing conditions.
Species
Human
Curated Selection
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