MPL Protein (C-His, Mouse)

Product Specifications

Abbreviation

MPL

Synonyms

C-mpl, CD110, hlb219, Mpl, TPO-R, Tpor

Host

HEK 293

Tag

C-His

Endotoxin

< 1.0 EU per μg protein as determined by the LAL method.

Purity

≥ 95 % as determined by SDS-PAGE. ≥ 95 % as determined by SEC-HPLC.

Bioactivity

Recombinant Mouse C-MPL Protein (His Tag) (Cat: 5A7679-M08H1) immobilized on CM5 chip, can bind Recombinant Human Thrombopoietin / THPO Protein (His Tag) (Cat: 10381-H08H1) with an affinity constant of 14.900 nM as determined in an SPR assay (Biacore 8K) (QC tested) .

Function

Met1-Trp482

Molecular Weight

The recombinant Mouse MPL consists of 468 amino acids and predicts a molecular mass of 52.64 kDa. It migrates as an approximately 59.61 kDa band in SDS-PAGE under reducing conditions.