MET Protein (C-His, Mouse)
Product Specifications
Abbreviation
MET
Synonyms
C-Met, HGF, HGFR, Met, Par4
Host
HEK 293
Tag
C-His
Endotoxin
< 1.0 EU per μg of the protein as determined by the LAL method
Purity
≥ 90 % as determined by SDS-PAGE. ≥ 90 % as determined by SEC-HPLC.
Bioactivity
1.Immobilized HGF Protein, Mouse, Recombinant (Cat:50038-MNAH) at 2 μg/mL (100 μL/well) can bind c-MET Protein, Mouse, Recombinant (ECD, His Tag) (Cat:50622-M08H), the EC50 is 80-400 ng/mL (Routinely tested) . 2.Immobilized Recombinant Human HGF Protein (Cat: 10463-HNAS) at 5 μg/mL (100 μL/well) can bind Recombinant Mouse c-MET / HGFR Protein (ECD, His Tag) (Cat: 50622-M08H), the EC50 is 0.5-3 ng/mL (QC tested) .
Function
Met1-Asn929
Molecular Weight
The recombinant mouse Met is a heterodimer composed of the proteolytically cleaved α and β subunits. The α and β heterodimer consists of 916 amino acids and has a predicted molecular mass of 102 (α =32 + β=70) kDa. The apparent molecular mass of the rmMET heterodimer thus is approximately 41.8 kDa and 87.2 kDa respectively in SDS-PAGE under reducing conditions due to glycosylation.
Species
Mouse
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FIG4, CT (FIG4, KIAA0274, SAC3, Polyphosphoinositide phosphatase, Phosphatidylinositol 3,5-bisphosphate 5-phosphatase, SAC domain-containing protein 3) (APC)
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