MET Protein (C-His, Mouse)

Product Specifications

Abbreviation

MET

Synonyms

C-Met, HGF, HGFR, Met, Par4

Host

HEK 293

Tag

C-His

Endotoxin

< 1.0 EU per μg of the protein as determined by the LAL method

Purity

≥ 90 % as determined by SDS-PAGE. ≥ 90 % as determined by SEC-HPLC.

Bioactivity

1.Immobilized HGF Protein, Mouse, Recombinant (Cat:50038-MNAH) at 2 μg/mL (100 μL/well) can bind c-MET Protein, Mouse, Recombinant (ECD, His Tag) (Cat:50622-M08H), the EC50 is 80-400 ng/mL (Routinely tested) . 2.Immobilized Recombinant Human HGF Protein (Cat: 10463-HNAS) at 5 μg/mL (100 μL/well) can bind Recombinant Mouse c-MET / HGFR Protein (ECD, His Tag) (Cat: 50622-M08H), the EC50 is 0.5-3 ng/mL (QC tested) .

Function

Met1-Asn929

Molecular Weight

The recombinant mouse Met is a heterodimer composed of the proteolytically cleaved α and β subunits. The α and β heterodimer consists of 916 amino acids and has a predicted molecular mass of 102 (α =32 + β=70) kDa. The apparent molecular mass of the rmMET heterodimer thus is approximately 41.8 kDa and 87.2 kDa respectively in SDS-PAGE under reducing conditions due to glycosylation.

Species

Mouse