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LRP6 Protein (C-human IgG1-Fc, Human)

Product Specifications

Abbreviation

LRP6

Synonyms

ADCAD2, STHAG7

Host

HEK 293

Tag

C-human IgG1-Fc

Endotoxin

< 1.0 EU per μg protein as determined by the LAL method.

Purity

≥ 85 % as determined by SDS-PAGE.

Bioactivity

1.Immobilized Recombinant Human Sclerostin / SOST Protein (His Tag), Biotinylated (Cat: 10593-H07H-B) at 2 μg/mL (100 μl/well) on streptavidin precoated (2 μg/mL, 100 μL/well) can bind Recombinant Human LRP-6 Protein (Fc Tag) (Cat: 11968-H02H1), the EC50 is 30-100 ng/mL. 2.Loaded Recombinant Human LRP-6 Protein, Fc Tag (Cat. No. 11968-H02H1) on proA Biosensor, can bind Recombinant Human SOST/Sclerostin Protein, His Tag (Cat. No. 10593-H07H) with an affinity constant of 10.500 nM as determined in BLI assay (Sartorius Octet RED384) (QC tested) .

Function

Ala20-Pro630

Molecular Weight

It migrates as approximately 111.7 kDa band in SDS-PAGE under reducing conditions.

Species

Human

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