LIFR Protein (C-His, Mouse)

Product Specifications

Abbreviation

LIFR

Synonyms

A230075M04Rik, LIF, Lifr

Host

HEK 293

Tag

C-His

Endotoxin

< 1.0 EU per μg of the protein as determined by the LAL method

Purity

> 95 % as determined by SDS-PAGE

Bioactivity

1. Measured by its ability to bind mouse LIF-Fc (Cat:50755-M02H) in a functional ELISA. 2. Measured by its ability to inhibit the Recombinant Human LIF mediated inhibition in the M1 mouse myeloid leukemia cells. The ED50 for this effect is typically 10-60ng/mL in the presence of 2 ng/mL recombinant human LIF.

Function

Met1-Ser828

Molecular Weight

The recombinant mouse LIFR consists of 796 amino acids and has a predicted molecular mass of 90 kDa. In SDS-PAGE under reducing conditions, the apparent molecular mass of rm LIFR is approximately 110-120 kDa due to glycosylation.