LEPR Protein (C-His, Human)

Product Specifications

Abbreviation

LEPR

Synonyms

CD295, DB, LEP-R, LEPRD, OB-R, OBR

Host

HEK 293

Tag

C-His

Endotoxin

< 1.0 EU per μg of the protein as determined by the LAL method

Purity

≥ 95 % as determined by SDS-PAGE. ≥ 90 % as determined by SEC-HPLC.

Bioactivity

Measured by its binding ability in a functional ELISA . Immobilized human Leptin at 5 μg/ml (100 μl/well) can bind human Leptin receptor with a linear range of 0.032-4.0 μg/ml .

Function

Met1-Asp839

Molecular Weight

The recombinant human LEPR consists of 829 amino acids and has a predicted molecular mass of 95 kDa. In SDS-PAGE under reducing conditions, the apparent molecular mass of rh LEPR is approximately 130-140 kDa due to glycosylation.