LAG3 Protein (C-human IgG1-Fc, Human)

Product Specifications

Abbreviation

LAG3

Synonyms

CD223, FDC

Host

HEK 293

Tag

C-human IgG1-Fc

Endotoxin

< 1.0 EU per μg protein as determined by the LAL method.

Purity

≥ 95 % as determined by SDS-PAGE. ≥ 85 % as determined by SEC-HPLC.

Bioactivity

Immobilized LAG3 Protein, Human, Recombinant (ECD, hFc Tag) (Cat:16498-H02H) at 2 μg/mL (100 μL/well) can bind Anti-LAG3 (BMS) -IgG4 Antibody (Relatlimab), the EC50 is 8-40ng/mL.

Function

Met1-Leu450

Molecular Weight

The recombinant human LAG3 consists of 666 amino acids and predicts a molecular mass of 72.9 kDa. As a result of glycosylation, it migrates as an approximately 84.19 KDa band in SDS-PAGE under reducing conditions.